BACKGROUND. It is a rare tumor which comprises 1% of all ovarian tumors and 2.7% of all dermoid tumors. Author information: (1)From the *Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, †Nuclear Medicine, Department of Radiology, and ‡Department of Pathology, University of Michigan, Ann Arbor, MI. In the wall of the cysts, small groups of thyroid follicles are also present. Malignant SO is extremely rare and seen in about 5% of cases (19 cases reported from 1990-2008). To reach the diagnosis of a struma ovarii, the tumor must either composed in more than 50% by thyroid component or with less The clinical records, CT and MRI features of twelve patients with pathologically proved SO were retrospectively analyzed. diagnosis of a malignant ovarian carcinoma preoperation. It is generally considered to account for less than 5% of mature teratomas. OBJECTIVE: To analyze the imaging features of Struma ovarii (SO), and to correlate the imaging results with the pathological findings so as to enhance the knowledge of the imaging diagnostics of this disease. Discussion. Struma ovarii or monodermal teratoma is a specialized ovarian neoplasm which mainly constitutes mature thyroid tissue. In summary, it is difficult to distinguish between struma ovarii and dermoid cysts on the basis of their sonographic appearance. Struma ovarii: This is a rare type of ovarian tumor that’s made mostly of thyroid tissue. The pathologic diagnosis of malignant transformation within ovarian dermoid cysts is challenging as the histo-logic criteria for cancer within the thyroid gland may not be predictive of metastatic potential in struma ovarii [4]. These patients, with mostly benign disease, often have more extensive surgery than necessary. OBJECTIVE: To analyze the imaging features of Struma ovarii (SO), and to correlate the imaging results with the pathological findings so as to enhance the knowledge of the imaging diagnostics of this disease. When hyperthyroidism is caused by an ectopic thyroid … We report an unusual case of incidental diagnosis of struma ovarii after thyroidectomy for thyroid … Struma ovarii is ectopic thyroid tissue associated with dermoid tumors or ovarian teratomas that can secrete excessive amounts of thyroid hormone and produce thyrotoxicosis. Struma ovarii usually presents in the fifth decade of live [6]. all struma [1, 2] with distant metastases being reported in 5–23% of patients with malignant struma ovarii [3]. Most commonly, they occur as part of a teratoma, but may occasionally be encountered with serous or mucinous cystadenomas. It is usually a benign lesion but sometimes, malignant transformation could be observed. [ 18 ] Read More (1-4) However, there is controversy regarding whether radical or conservative surgery should be practised, and what the optimum approach of surgical access should be. Struma Ovarii With Hyperthyroidism. Figure 1: Struma ovarii (low power) In this hyperemic ovary multiple collapsed cysts filled by colloid and lined by a single layer of thyreocytes are observed. Struma Ovarii (SO) is the most frequent monodermal ovarian teratoma and is defined as a teratoma composed primarily or exclusively of thyroid tissue. Struma ovarii is a rare ovarian neoplasm that often appears malignant on conventional imaging. Preoperative clinical diagnosis of struma ovarii, is very difficult. CONTEXT: Struma ovarii, a rare neoplasm, is a monophyletic teratoma composed of thyroid tissue. Nevertheless, Doppler flow may aid in the preoperative diagnosis of struma ovarii. To analyze the imaging features of Struma ovarii (SO), and to correlate the imaging results with the pathological findings so as to enhance the knowledge of the imaging diagnostics of this disease. Imaging features were compared with pathological results. Hormonal findings revealed increased thyroid function, but the … [1 ] Struma ovarii were first described in 1899 and comprise 1% of all ovarian tumors. The lungs lesions were confirmed to be follicular thyroid cancer by biopsy. It is usually a benign condition; METHODS: The clinical records, CT and MRI features of twelve patients with pathologically proved SO were retrospectively analyzed. Diagnosis by preoperative imaging studies were 8 dermoid cysts, while only 3 cases were diagnosed as struma ovarii. Matsuda et al9 reported on a 48-year-old woman who presented with symptoms of hyperthyroidism and an ovarian mass. The final histologic diagnosis was struma ovarii, 100% of the tumor was composed by thyroid tissue, malignancy was ruled out in the tumor and ascitic liquid.. 3. Prognosis of benign strumosis and malignant struma ovarii without metastases is good. Figure 2: Struma ovarii (high power) Small groups of … Preoperative diagnosis of struma ovarii is difficult as the symptoms, clinical presentation and image on ultrasound are often similar to that of ovarian carcinoma. Struma ovarii is a rare ovarian tumor defined by the presence of thyroid tissue comprising more than 50% of the overall mass. It contains about 2.7% of ovarian teratomas . Ovary tumor - Struma ovarii. A 50-year-old woman with abdominal distention and dyspnoea was referred to our hospital. The diagnosis of a cystic struma ovarii is usually made on histopathology. Historically, struma ovarii is managed via surgical removal of the ovarian cyst or mass, to enable a histological diagnosis to be made and to rule out ovarian malignancy. It is a typically … We present the cases of four women who were diagnosed with struma ovarii postoperatively. It most commonly occurs as part of a teratoma.1, 2 Although struma ovarii usually does not secrete thyroid hormones, there are cases in which it produces thyroid hormones, which results in hyperthyroidism. We performed TSHR staining in both the patient’s struma ovarii and in 3 cases of non-functioning struma ovarii. 2011; 36(5):627-31 (ISSN: 1432-0509) Shen J; Xia X; Lin Y; Zhu W; Yuan J. Struma ovarii is a rare ovarian germ-cell tumor containing thyroid tissue. Occasionally there are symptoms of hyperthyroidism. In the present patient, we confirmed the positive expression of CK19, TTF-1, and Tg in the tumor, which suggested a malignant process. Pseudo-Meigs’ syndrome with ascites, pleural effusion, and elevated serum CA 125 levels is much rarer and leads to misdiagnosis of ovarian cancer and unnecessary extended surgery. Some (5%) patients with struma ovarii present with symptoms of hyperthyroidism, absence of thyroid gland enlargement, an elevated thyroglobulin level, and a low thyroid radioiodine uptake. This diagnosis should be suggested in the differential diagnosis of patients with symptoms of thyroid disease and a normal thyroid gland. Blood flow signals, detected from the center of the echoic lesion, and low resistance to flow may be more common in struma ovarii. Diagnosis of Struma ovarii with medical imaging. [ 2-4 ] mature teratomas monodermal teratoma is a rare tumor which comprises 1 % of the tumors. Comprise 1 % of the ovarian tumors and 2-3 % of ovarian teratomas 2-4... 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